Key Takeaways

• Our Trybello Eyelash Growth Serum costs $39.95, combines a growth serum and a mascara on one tube, and is backed by free shipping on all orders.
• Nanolash costs about $59 for a 3 mL tube, though the brand says one tube can last four to six months, while GrandeLASH-MD is the lowest upfront at $36 for its 1 mL size.
  
• Trybello takes a gentler, hormone-free route to promote healthy eyelash and brow growth, while Nanolash and GrandeLASH-MD are prostaglandin-based.
  
• Our Trybello Eyelash Growth Serum is rated 4.8 across thousands of reviews; Nanolash is at about 4.1, while GrandeLASH-MD sits near 4.8.
• The Trybello Eyelash Growth Serum is the best pick for most people, as a prostaglandin-free, vegan option that pairs serum and mascara in one tube.

Nanolash vs GrandeLASH-MD vs Trybello Lash Serum: What are the Differences?

Nanolash, GrandeLASH-MD, and Trybello all set out to give you longer, fuller lashes, but they differ sharply on cost, formula, and how they get results. Our Trybello serum lands in the middle on price at $39.95, and it skips prostaglandins entirely in favor of a peptide-and-botanical blend.

Nanolash costs $59 a tube and leans on a prostaglandin analog to drive fast, dramatic change, while GrandeLASH-MD starts at $36 and also uses a prostaglandin, peptides, vitamins, and amino acids.

That difference in ingredient matter as the content of the formula you choose shapes the experience. Prostaglandin serums like Nanolash and GrandeLASH-MD often carry a higher chance of irritation and effects such as darkening around the eye. A peptide route, like the one in our Trybello serum, serves as a gentler daily routine that stays comfortable on sensitive eyes.

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• ✓ Gluten-free, fragrance-free, no parabens
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Trybello Eyelash Growth Serum

The Trybello Eyelash Growth Serum is formulated with grape seed extract, pumpkin seed extract, and panax ginseng.

At Trybello, we made our Eyelash Growth Serum for people who want noticeably fuller lashes but would rather skip the hormone-based ingredients many serums depend on. The standout feature is the format: our 2-in-1 version puts a nourishing growth serum and a volumizing mascara on opposite ends of one tube, so a single product both cares for your lashes and dresses them up. It's also vegan and cruelty-free.

Instead of forcing the lash cycle the way prostaglandin products do, our serum feeds and fortifies your existing lashes with a peptide and a mix of plant-based nutrients. That approach keeps it gentle enough for sensitive eyes while still working toward visibly denser lashes, and we stand behind every bottle with a results guarantee so there's nothing to lose by trying it.

Price

Our 2-in-1 Eyelash Growth Serum is $39.95, marked down from its usual $49.95, and every order ships free. Because that single price covers both a serum and a mascara, you're effectively buying two products in one, which makes it easier to justify than a serum alone at a similar cost. There's no subscription required, and the purchase is protected by our 60-day money-back growth guarantee.

Results

With daily use, once or twice a day, most people start to see longer, thicker-looking lashes over about four weeks, and the effect keeps improving the longer you stay with it. Since our formula stimulates the rejuvenation of your lash follicles and conditions rather than chemically speeding up growth, the change comes on gradually, which is exactly why our guarantee gives you a two-month window to see how your own lashes respond.

Reviews

Our lash and brow range has earned a large and enthusiastic customer base, with a rating close to 4.8 out of 5 across thousands of reviews. Shoppers most often mention the gentle, no-sting feel, the easy-to-control applicator, and the convenience of having serum and mascara in one tool. The common thread in the feedback matches how the formula works: the people happiest with their results are the ones who applied it consistently over several weeks.

Emily K, a Trybello user, praises the Eyelash Growth Serum for promoting the growth of full, healthy lashes.

Nanolash Eyelash Serum

Nanolash is a European lash brand whose serum is applied once daily along the upper lash line with a fine precision brush. (Image source: Nanolash)

Nanolash Eyelash Serum is a prostaglandin-based product, and that active ingredient is what drives the faster, more visible lengthening and darkening the brand is known for. Nanolash also sells a separate prostaglandin-free peptide version, so it's important to check which formula a listing refers to before ordering.

Price

Nanolash sits toward the higher end of the category, generally selling for $59 for a single 3 mL tube depending on the retailer. The brand notes that one tube can last roughly four to six months with daily use, which lowers the effective monthly cost if that holds for you. It's sold as a standalone serum, with no bundled mascara or built-in subscription discount.

Results

Nanolash says first results tend to appear after about two weeks of daily use, with lashes up to 50% longer after 30 days, followed by a lighter maintenance routine of two to three applications a week. The quicker visible effect ties directly to the prostaglandin active, and results still depend on daily consistency.

Reviews

Nanolash holds a mid-range rating of around 4.1 across 400-plus reviews on Amazon. Positive reviewers highlight noticeable length and fullness over a couple of months, while the recurring complaints center on eye irritation and, for some, a wand applicator that wears out or a repurchased tube that felt less effective than an earlier one. Overall, the reviews suggest results and tolerance vary quite a bit from person to person.

A Nanolash user reports longer and fuller lashes, but darker under eyes (image source: Amazon).

GrandeLASH-MD Lash Serum

GrandeLASH-MD is a widely sold serum from Grande Cosmetics, marketed as the number-one lash and brow serum brand in the US. (Image source: Grande Cosmetics)

GrandeLASH-MD Lash Serum is applied once daily as a single stroke along the upper lash line, like a thin eyeliner, and works through a prostaglandin analog paired with peptides, vitamins, and amino acids. It's ophthalmologist-tested and compatible with contacts and lash extensions, though it is not vegan, since the formula contains a small amount of honey.

Price

GrandeLASH-MD is competitively priced for a prostaglandin serum, at $68 for the 2 mL tube, which Grande describes as a three-month supply. A smaller 1 mL six-week supply runs $36.

Results

Grande advertises longer, thicker-looking lashes in about four to six weeks, with fuller improvement by the three-month mark, and recommends continued use to maintain the effect. Its 12-week consumer study of 30 subjects reported that 91% saw longer-looking lashes, 94% saw healthier-looking lashes, and 97% saw more visible lashes.

As a prostaglandin-based product, the change tends to come faster than with peptide-only serums, though results still vary and require ongoing daily use.

Reviews

GrandeLASH-MD holds roughly 4.8 out of 5 across thousands of reviews on Grande's own site. Users frequently report visible length and fullness within several weeks, with many long-term buyers repurchasing.

The most common criticisms are occasional eye irritation or sensitivity and packaging that makes it hard to tell how much product is left, both consistent with the brand's own guidance that a small share of users experience initial sensitivity.

A user reports longer lash length but increased eye irritation after using GrandeLASH-MD (image source: Grande Cosmetics).

Nanolash vs GrandeLASH-MD vs Trybello: Comparison Table

Why Trybello Is the Smarter Buy for Everyday Lash Care

Across these three, the decision comes down to what you're optimizing for. If you want the fastest possible change and accept the trade-offs of a prostaglandin, Nanolash and GrandeLASH-MD make that case, one at a premium price, the other at a lower entry cost. But speed isn't the only thing worth paying for, and for a lot of people it isn't even the main thing.

Our Trybello Eyelash Growth Serum wins on the balance of value, comfort, and convenience. It's the only option here that hands you a growth serum and a volumizing mascara on one tube. That way, lash care folds into your daily routine, and the same product works across your upper lashes, lower lashes, and brows. Try our Trybello Eyelash Growth Serum to see the difference.

Frequently Asked Questions (FAQs)