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RevitaLash vs GrandeLASH-MD vs Trybello Lash Serum: Ingredients, Results & Side Effects

BY TRYBELLO

Aug 20, 2025

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Key Takeaways

  • Lashes protect the eyes and enhance beauty, but stress, aging, and cosmetic overuse can cause thinning and breakage, making lash serums a popular solution.
  • RevitaLash and GrandeLASH-MD contain prostaglandin analogues for fast growth (4–8 weeks) but may cause irritation, pigmentation changes, or even rare iris color shifts. Trybello avoids these hormones, using plant-based peptides, vitamins, and extracts for gentler, gradual improvement in 2–4 weeks.
  • RevitaLash blends peptides, biotin, and botanicals for strengthening; GrandeLASH-MD combines prostaglandins with hydrating agents for rapid length and fullness; Trybello focuses on natural conditioning and long-term lash health without harsh chemicals.
  • Selection depends on sensitivity, desired speed of results, and long-term safety. Prostaglandin serums offer faster drama, while prostaglandin-free options like Trybello prioritize gentle, sustainable lash enhancement.
  • Our Bello Eyelash Serum delivers visible results in just 2 weeks using 100% natural, prostaglandin-free ingredients like Pentapeptide-17, Panax Ginseng, and biotin, backed by our industry-leading 120-Day Growth Guarantee and trusted by over 40,000 customers.

Why Lash Wellness Deserves More Attention

Eyes might steal the show, but lashes are the frame that gives them their wow factor, while quietly shielding them from dust and debris. Over time, stress, aging, heavy mascara use, curling, and lash extensions can leave them looking sparse or fragile.

That’s where eyelash serums step in. These targeted treatments nourish and condition lashes, helping them appear longer, stronger, and fuller. The trick is finding one that delivers results without compromising safety, so your lashes stay healthy as well as beautiful.

“100% Natural Serum Delivers Visibly Longer, Fuller Lashes in Just 30 Days. The Safe Alternative to Expensive Extensions!"

Transform your lashes naturally with our plant-based formula—free from oils, hormones, silicones, and harsh chemicals that can damage delicate eye area.

Proven Natural Ingredients

  • • Panax Ginseng – Revitalizes hair follicles for accelerated lash growth
  • • Pumpkin Seed Extract – Restores and strengthens your natural lashes from root to tip
  • • Grape Seed Extract – Reduces lash loss and breakage for fuller, thicker lashes

See Your Transformation Week by Week

  • • Week 1: Fuller lashes begin to emerge
  • • Week 2: Consistency builds momentum—stay committed!
  • • Week 3: Noticeable growth becomes visible
  • • Week 4: Enjoy visibly longer, fuller, and naturally beautiful lashes

Clean Beauty You Can Trust

  • • Gluten-free and fragrance-free formula
  • • No parabens, PEGs, or artificial additives
  • • Works on both upper and lower lash lines, plus eyebrows!
  • • Simple daily application with precision applicator

Risk-Free 60-Day Trial

Guarantee No dramatic results after 2 months? Get 100% of your money back—no questions asked.

Before and After Lashes
Testimonial Image

TRY OUR BELLO EYELASH SERUM NOW →


A Closer Look at Each Serum's Formula

RevitaLash

RevitaLash uses a combination of peptides, biotin, and naturally derived plant extracts like green tea, calendula, and ginseng. It also includes a prostaglandin analogue, a synthetic compound originally used in glaucoma medication, known for its lash-lengthening effects. While the combination can deliver remarkable thickness and strength, the inclusion of prostaglandin analogues means there’s a potential risk of side effects such as redness or pigmentation changes.

Additionally, it contains antioxidant-rich botanicals aimed at shielding lashes from environmental stressors and soothing the delicate skin around the lash line.

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RevitaLash serums can deliver impressive results but require careful consideration of potential side effects before use.

GrandeLASH-MD

GrandeLASH-MD has built its reputation on fast, dramatic results. Like RevitaLash, it also relies heavily on isopropyl cloprostenate, a prostaglandin analogue, to stimulate lash growth at the follicular level. This is paired with hydrating allies like hyaluronic acid and botanical extracts such as grape seed, aloe vera, and honey, which help condition lashes and keep them flexible.

Many users report results in just four to six weeks. However, the same prostaglandin-based approach that fuels its rapid enhancement can also lead to adverse effects, including eyelid darkening, increased pigmentation, and in rare cases, changes to iris color, particularly for individuals with lighter eyes.

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Fast-acting lash serums like GrandeLASH-MD can deliver dramatic results in weeks but come with important safety considerations.

Trybello Lash Serum

Trybello Lash Serum is formulated with a blend of gentle yet effective ingredients. Key components include purified water, pumpkin (Cucurbita pepo) seed extract, sodium chloride, grape (Vitis vinifera) seed extract, citric acid, Panax ginseng extract, Swertia japonica extract, pentapeptide-17, and hyaluronic acid. It also features vitamins such as Vitamin E (tocopherol), Vitamin B7 (biotin), and Vitamin B5 (panthenol).

In addition, natural waxes like carnauba wax and candelilla cera add emollient properties, while tocopherols (a form of Vitamin E) further help support overall lash and scalp health. The formula is focused on conditioning and strengthening lashes without harsh prostaglandin analogues, making it suitable for sensitive eyes.

The result: a formula designed to be gentle enough for sensitive eyes while still producing visibly thicker, healthier lashes, often within 2–4 weeks of consistent use.

Try Bello Eyelash Serum in a pink tube with an applicator wand.png__PID:55e16898-24c5-497b-8379-df9434f384fb

Trybello’s gentle, and naturally-formulated lash serums offer effective results without the harsh ingredients that can cause unwanted side effects.

What People Are Saying: Real-World Results

RevitaLash Feedback

Many users notice thicker, stronger lashes in about eight weeks, with some crediting it for bringing life back to lashes damaged by extensions or heavy makeup. On the flip side, a few mention redness, irritation, or lashes growing in unusual directions, and those with sensitive skin sometimes see pigment changes around the lash line.

Screenshot of a 3-star review of RevitaLash.png__PID:4d4ad0a6-07d7-4a93-b295-154a20c7ea8d

Real customer reviews highlight the common trade-off with powerful lash serums between dramatic results and potential side effects.

GrandeLASH-MD Feedback

This one earns praise for quick results, often within four to six weeks, boosting both length and fullness. Some call it the most effective lash enhancer they’ve tried. However, side effects like eyelid darkening, brittleness, and even rare permanent iris color changes can be deal-breakers, especially when paired with occasional irritation.

Trybello Feedback

Users often spot richer-looking lashes in just a few weeks, with noticeable volume and softness over time. Lashes stay flexible, never brittle, and there are little to no reports of irritation or pigment darkening, making it a gentle choice for sensitive eyes. Its standout trait is a prostaglandin-free, plant-based formula that focuses on lasting lash health as much as instant glamour.

Screenshot of a 5-star review of Trybello.png__PID:4300dd89-4207-4337-b438-073984b5c3ee

Positive customer reviews highlight how gentle Trybello's plant-based formulas can deliver effective lash growth without the irritation issues.

Safety and Sensitivity Considerations

One of the most important differences between these products is the risk profile.

  • Prostaglandin-based serums (RevitaLash, GrandeLASH-MD) have strong track records for rapid visible improvement but also carry the possibility, however small, of more serious side effects, including skin darkening and eye color changes.
  • Prostaglandin-free serums like Trybello offer a gentler, more gradual approach, lessening the likelihood of irritation or cosmetic side effects while still delivering visible lash thickening and strength.

Head-to-Head Comparison

FeatureRevitaLash AdvancedGrandeLASH-MDTrybello Lash Serum 
Main ActivePeptides + Prostaglandin analogueProstaglandin analogue + Amino AcidsPlant-based peptides + Biotin + Oils
Result Timeline8 weeks4–6 weeks2–4 weeks, continued improvement
ProsStrengthens, improves curl, rich botanicalsFast dramatic results, hydrating agentsGentle for sensitive eyes, prostaglandin-free, nourishing
ConsPossible irritation, pigment changesPigment/iris change risk, irritation possibleNone reported, gradual enhancement
Overall FocusLash conditioning + visible thickeningFast, dramatic length + thicknessSafe, long-term lash wellness + volume

Why Trybello Lash Serum Is Your Best Choice

Woman holding a tube of Trybello Lash Serum near her temple.png__PID:b0c49011-1983-45a5-bf64-38df6feba46e

Choosing our gentle, plant-based lash serum means you can enhance your natural beauty safely without worrying about harmful side effects.

Beautiful, healthy lashes should never come at the expense of eye health. That’s why we created Trybello, a US-based brand dedicated to delivering safe, natural, and effective lash enhancement backed by science. Our Eyelash Serum uses a 100% plant-based formula that delivers visible results in as little as 30 days, avoiding the risks linked to prostaglandin analogues used by many competitors. Each ingredient is chosen for performance, including Pentapeptide-17 to stimulate growth, Panax Ginseng to revitalize follicles, Pumpkin Seed Extract to strengthen, Grape Seed Extract for antioxidant protection, and biotin with vitamins to support lasting lash health.

We take a complete approach to eye beauty. Alongside our lash serum, we offer a matching brow serum for fuller brows in just weeks, a hydrating mascara that nourishes as it adds volume, and bundles that combine lash, brow, hair, and mascara products for total enhancement. Our hair wellness line also supports growth and strength with solutions like Hair Helper Spray, gummies for internal nourishment, growth shampoos and conditioners, and tools to boost results.

Safety is at the heart of our formulas. Every product is prostaglandin-free, vegan, cruelty-free, and free of parabens, PEGs, silicones, and synthetic fragrances. Ophthalmologist testing ensures they’re safe for sensitive eyes and contact lens wearers. Application is simple: cleanse, apply along the lash line, let it dry, and repeat daily for the best results.

We stand by our 120-Day Growth Guarantee, so your purchase is truly risk-free. If you want longer, fuller lashes and complete peace of mind, our natural formula delivers beauty that lasts.

TRY BELLO LASH SERUM TODAY!

Frequently Asked Questions (FAQs)

Can lash serums permanently change my eye color?

Yes, prostaglandin-containing serums (like RevitaLash and GrandeLASH-MD) have documented cases of permanent iris darkening, especially in people with lighter eyes. This is why many users are switching to prostaglandin-free alternatives that eliminate this risk entirely.

Are lash serums safe to use with contact lenses?

Most lash serums claim compatibility with contact lenses, but prostaglandin-based formulas carry higher risks of eye irritation and dry eyes. Always wait for the serum to completely dry before inserting contacts, and consider prostaglandin-free options if you experience any discomfort.

What should I do if I experience side effects from my lash serum?

Stop using the product immediately and consult with an eye care professional, especially if you notice redness, swelling, darkening around the eyes, or changes in vision. Document any changes with photos, as some effects from prostaglandin serums can be permanent.

Can I use lash serum on my eyebrows, too?

Many lash serums can be safely applied to eyebrows, but check the specific product instructions. The skin around the eyebrows is generally less sensitive than the eyelid area, making it more tolerant of active ingredients. However, the same safety considerations regarding prostaglandins still apply.

What ingredients make Trybello's lash serum prostaglandin-free?

Our Eyelash Serum is formulated with Pentapeptide-17 (an advanced peptide), Panax Ginseng Extract for follicle revitalization, Pumpkin Seed Extract for restoration, Grape Seed Extract for antioxidant protection, and Biotin for strength. We also include Hyaluronic Acid for hydration and natural waxes for smooth application. The serum is completely free of oils, hormones, silicones, PEGs, parabens, perfumes, and gluten, making it ideal for sensitive eyes.

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