Key Takeaways

• Anagain™ and Capixyl™ target key pathways to reduce shedding, extend growth phase, improve circulation, and support overall hair density.
• Anagain™, from pea sprouts, stimulates follicles and reduces the resting phase, helping with general thinning and stress-related hair loss.
  
• Capixyl™ lowers DHT, reduces scalp inflammation, and strengthens follicles, making it ideal for hormone-driven or pattern hair loss.
  
• Consistent use, proper application, complementary treatments, nutrition, and stress management maximize hair growth and follicle health.
• Pairing Trybello Hair Repair & Anti-Stress Gummies with Bello Hair Helper Spray Plus delivers dual-action benefits: the gummies reduce stress and strengthen follicles, while the spray stimulates faster, denser, and fuller hair growth.

Hair Loss Solutions: What Actually Works?

The hair loss market is crowded with products claiming results, but only a few ingredients are backed by scientific evidence. Beyond minoxidil and finasteride, peptide-based compounds like Anagain™ and Capixyl™ are emerging as effective options for thinning hair. They target key biological pathways that support hair growth and retention.

Effective solutions typically work by extending the growth (anagen) phase, shortening the resting (telogen) phase, reducing follicle inflammation, improving scalp circulation, or inhibiting DHT. The best treatments often combine multiple mechanisms for stronger results.

Anagain™ and Capixyl™ stand out due to their clinical research. Studies show measurable improvements in hair density and reduced shedding, proving their real-world effectiveness when used consistently in properly formulated products.

“Doctor-Approved Natural Spray Rapidly Boosts Growth & Thickness.
Why 100,000+ Women Are Switching to The TryBello All-Natural Solution!"

Join over 100,000 happy customers who’ve transformed their hair with our natural, doctor-formulated spray—rated 4.8/5 by more than 40,000 real users.

Proven Natural Ingredients

• • Caffeine Extract – Naturally blocks DHT and boosts blood flow to hair follicles
• • Biotin – Absorbs directly through the scalp for maximum results—no pills needed
• • Castor Oil – Soothes inflammation and locks in deep, lasting moisture
• • Rice Water Extract – Packed with proteins and minerals to strengthen hair and reduce shedding

Get Visible Results in 12 Weeks

• • Up to 45% increase in hair thickness
• • Reduces shedding and unclogs hair-draining nightmares
• • Supports regrowth in thinning areas
• • Leaves hair soft, shiny, and full of life

Ironclad 120-Day Growth Guarantee

No results after 4 months? Get 100% of your money back—no questions asked.

TRY YOUR BELLO HAIR HELPER SPRAY NOW →

What Is Anagain™? The Science Behind This Hair Growth Ingredient

Anagain™ is a natural extract from organic pea sprouts (Pisum sativum), developed by Mibelle Biochemistry in Switzerland. It’s known for reactivating hair growth at the follicle level, thanks to its unique mix of bioactive compounds, including biotin, L-arginine, and plant isoflavones.

Key Active Components

Biotin (vitamin B7) supports keratin production, L-arginine improves blood flow to follicles, and plant compounds regulate signaling proteins in dermal papilla cells, all promoting healthier hair growth.

Anagain™ works at the follicle level, keeping more hairs in the growth phase for fuller-looking hair.

How Anagain™ Works

Anagain™ stimulates dermal papilla cells, increasing FGF-7 to boost follicle proliferation and noggin to reduce the telogen (resting) phase. This keeps more hairs in the growth (anagen) phase longer. Clinical studies show that applying a 2% Anagain™ gel twice daily for 2 months decreases resting hairs and increases growing hairs, supporting thicker, fuller-looking hair over time.

What Is Capixyl? Breaking Down This Popular Treatment

Capixyl™ is a leading peptide-based hair loss solution, combining acetyl tetrapeptide-3 with red clover extract (Trifolium pratense) to tackle multiple causes of thinning hair. This dual-action formula supports follicle health and stimulates new growth.

Red Clover Extract and Peptide Synergy

Red clover extract provides Biochanin A, an isoflavone that inhibits 5-alpha-reductase, reducing DHT levels, while acetyl tetrapeptide-3 strengthens hair anchoring and boosts extracellular matrix proteins. Together, they address hormonal and structural factors in hair loss more effectively than either component alone.

How Capixyl™ Works

Capixyl™ lowers DHT, reduces scalp inflammation, and reinforces follicle support. Clinical studies show that Redensyl, Capixyl, and Procapil (RCP) outperform 5% minoxidil in promoting hair growth and improving hair density in men with androgenetic alopecia.

Head-to-Head Comparison: Anagain™ vs Capixyl™

When choosing between Anagain™ and Capixyl™, consider hair loss type, expected results, cost, and ease of use. Each offers unique benefits depending on your needs.

Effectiveness for Different Hair Loss Types

Anagain™ works well for general thinning, stress-related shedding, seasonal hair loss, and age-related thinning. It extends the anagen (growth) phase and reduces premature shedding, making it a natural, plant-based option.

Capixyl™ is best for hormone-related or pattern hair loss. Red clover extract helps reduce DHT, while the peptide strengthens follicles and reduces scalp inflammation. It’s ideal for receding hairlines, crown thinning, and other androgenetic hair loss patterns.

Speed of Results

Both ingredients require consistent use over several months. Anagain™ shows reduced shedding in 6–8 weeks, with visible improvements in density around three months. Full results generally appear after 4–6 months of twice-daily use. Capixyl™ follows a similar timeline, though some professional-grade formulations may work with once-daily application.

Value for Money

Capixyl™ formulations are generally considered a premium option due to the complexity of peptide synthesis. Both ingredients are more effective in higher-concentration, professional-grade products, which often deliver better long-term results and reduce the need for additional treatments.

Ease of Use and Application

Anagain™ comes as lightweight, fast-absorbing serums with minimal residue, easy to style over, typically applied twice daily. Capixyl™ is available in serums, foams, and intensive treatments. Some formulations may leave a noticeable residue, but professional versions often require less frequent use while remaining effective.

Potential Side Effects and Safety Concerns

Both Anagain™ and Capixyl™ have strong safety profiles compared to pharmaceutical hair loss treatments, but mild reactions can occur. Understanding potential side effects helps you monitor your response and decide if these products are suitable. Most reactions are temporary and often subside as the scalp adapts.

Common Anagain™ Side Effects

Anagain™ is generally well-tolerated. Some users may experience mild scalp tingling, temporary redness, or dryness during the first few weeks. Tingling or redness usually fades within 15–30 minutes, and dryness can often be managed with a gentle, hydrating shampoo. A small number of users may experience initial shedding, where more hairs fall out temporarily as old hairs make way for new growth. This typically resolves within 2–3 weeks and indicates the hair cycle is being activated. Rarely, contact dermatitis may occur.

Combination treatments address multiple hair loss pathways for stronger, long-lasting results.

Reported Capixyl™ Reactions

Capixyl™ is also highly tolerable, with only few users reporting mild scalp irritation, temporary redness, or itching. Some may notice a brief warming or tingling sensation, which reflects increased microcirculation and nutrient delivery to follicles. Most reactions resolve within a few weeks of consistent use.

Who Should Avoid These Treatments

Individuals with allergies to pea proteins should avoid Anagain™, while those sensitive to red clover or peptides should approach Capixyl™ cautiously. Open wounds, sunburned scalps, or active infections should be treated before use. Pregnant or breastfeeding women should consult a healthcare provider, and those with severe scalp conditions like psoriasis or seborrheic dermatitis should seek guidance before starting treatment.

Comparison of Key Hair Growth Ingredients: Anagain™ vs Capixyl

How to Maximize Results from Either Treatment

Getting the best results with Anagain™ or Capixyl™ requires more than applying the product. Strategic application, complementary treatments, and lifestyle habits can improve hair density and overall follicle health.

Optimal Application Techniques

Apply to a clean, dry scalp, parting hair in sections and applying directly to the scalp. Massage for 60–90 seconds to boost absorption and blood flow. Apply consistently at the same time daily, ideally in the evening. For twice-daily use, leave at least 8 hours between applications and avoid heavy styling products for 1–2 hours afterward.

Complementary Treatments

Microneedling 1–2 times per week can enhance absorption, and low-level laser therapy (LLLT) 3–4 times weekly may stimulate follicles further. Nutritional supplements with biotin, zinc, vitamin D, iron, or marine proteins can support hair growth and complement topical treatments.

Diet and Lifestyle Factors

Stress can hinder results, so practices like meditation, regular exercise, and adequate sleep help optimize hormonal balance and scalp circulation. A diet rich in protein, omega-3s, antioxidants, and iron supports growth, while reducing processed foods helps limit inflammation. Proper hydration ensures nutrient delivery to follicles.

Medications and environmental factors may also affect results. Consult a healthcare provider for hair-friendly alternatives and minimize exposure to heat, pollutants, and harsh styling practices to maintain an optimal scalp environment.

The Final Verdict: Which One Should You Choose?

Choosing between Anagain™ and Capixyl™ depends on your type of hair loss and treatment goals. For androgenetic alopecia (pattern hair loss) with receding hairlines or crown thinning, Capixyl™ is generally more effective due to its DHT-inhibiting properties and follicle-strengthening peptides. Clinical studies show it can significantly improve the anagen/telogen ratio, making it ideal for hormone-driven hair loss.

Anagain™ is better suited for diffuse thinning, stress- or nutrition-related shedding, seasonal hair loss, or for those preferring plant-based formulations with minimal synthetic ingredients.

Combination products containing both Anagain™ and Capixyl™, sometimes with other actives like Redensyl or Procapil, can provide comprehensive coverage of multiple hair growth pathways. While these formulations are premium, they often deliver superior results for persistent or complex hair loss.

Consult a dermatologist if hair loss is sudden, severe, or unresponsive to over-the-counter treatments. Both ingredients require consistent use over several months to see visible improvements, and maintenance is necessary to sustain results. Documenting progress with monthly photos can help track changes more accurately.

Maximize Hair Growth with Trybello

For a complete, science-backed approach to hair health, combining Trybello Hair Repair & Anti-Stress Gummies with Bello Hair Helper Spray Plus delivers dual-action results—tackling hair loss from the inside and out.

Daily use of Trybello Gummies helps balance hormones and reduce cortisol for healthier hair.

Our gummies are formulated for stress-related shedding, featuring Anagain™, L-theanine, zinc, and B-complex vitamins to strengthen follicles, support hormone balance, reduce cortisol, and improve overall hair fullness. Clinically proven to increase hair thickness and volume, they’re vegan, sugar-free, and safe for daily use. Consistent use can show noticeable improvements in as little as 3 weeks, with up to 20% increased fullness after 12 weeks.

Combined internal and topical care addresses multiple causes of thinning hair effectively.

The Hair Helper Spray Plus, enhanced with Capixyl™, biotin, and caffeine, targets hair at the follicle level. It reduces DHT, strengthens follicle anchoring, and stimulates faster, denser growth. Visible improvements can appear in as fast as four weeks, with long-term results achieved through daily, consistent application. Free from hormones, parabens, silicones, and gluten, the spray complements the gummies for a holistic, non-toxic regimen.

Together, these products offer a premium, US-made solution for thicker, fuller, and healthier hair. Backed by a 120-day risk-free trial, you can confidently support hair growth and fight stress-related thinning with Trybello’s proven formulas.

Start your journey to fuller hair today!

Frequently Asked Questions (FAQs)