PRP vs Microneedling for Hair Loss: Results, Cost & Side Effects
BY TRYBELLO
Jul 22, 2025

Key Takeaways
- PRP and microneedling stimulate hair regrowth through different mechanisms. PRP uses your blood's growth factors while microneedling creates controlled micro-injuries to trigger healing responses.
- Microneedling can produce similar hair regrowth results to PRP therapy, but at a significantly lower cost (microneedling devices start at $30–200 vs. $500–2500 per PRP session).
- Side effects are typically mild and temporary for both treatments, with microneedling causing short-term redness and irritation, while PRP may cause minor swelling at injection sites.
- TryBello's Hair Helper Spray is a convenient, affordable alternative that complements these clinical treatments, featuring natural ingredients like biotin, castor oil, and caffeine that promote hair growth.
PRP vs Microneedling Basics
Understanding the fundamental differences between these two popular hair restoration methods will help you determine which might be better suited for you.
What is PRP?

PRP therapy uses the platelets in your blood to help regrow hair.
Platelet-Rich Plasma (PRP) therapy is a regenerative treatment that harnesses the natural healing power within your own blood. PRP therapy begins with a standard blood draw, similar to what you'd experience during a routine lab test. This blood sample is then placed in a centrifuge that spins at high speeds to separate the components, concentrating the platelets that contain growth factors.
These concentrated platelets contain proteins that play a crucial role in healing and tissue regeneration. When injected into the scalp, they deliver growth factors directly to your hair follicles, potentially stimulating them to enter an active growth phase. The growth factors work by increasing blood supply to the follicles, thickening hair shafts, and extending the growth phase of the hair cycle.
How Microneedling Works
Microneedling, also known as collagen induction therapy, involves using a specialized device equipped with fine needles to create thousands of microscopic punctures in the scalp. These tiny injuries are superficial but significant enough to trigger the body's wound healing response, which includes increased blood flow and the release of growth factors naturally present in your body.
This controlled injury process stimulates collagen and elastin production, which can strengthen hair follicles and create a healthier environment for hair growth. Additionally, the micro-channels created during treatment can enhance the absorption of topical hair growth products applied afterward, potentially boosting their effectiveness. The needles typically range from 0.5 mm to 1.5 mm in length, but may need to go deeper depending on your hair.
Target Hair Loss Conditions
Both PRP and microneedling are primarily used to address androgenetic alopecia, the most common form of hair loss affecting both men and women.
Note that neither treatment is typically recommended for scarring alopecias (like lichen planopilaris or frontal fibrosing alopecia) or for completely bald areas where follicles are no longer viable. The best candidates are those in early to moderate stages of hair loss who still have functioning hair follicles that can be stimulated.
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Hair Growth Result Comparison
PRP Study Results
Multiple clinical trials have demonstrated PRP's ability to improve hair parameters in patients with androgenetic alopecia. A study found that patients receiving PRP treatments experienced a 33.3 hair per square centimeter mean increase in density after three PRP sessions.
The effectiveness of PRP appears to be dose-dependent, with protocols involving multiple treatment sessions (typically 3–4 initial treatments spaced 4–6 weeks apart) showing better outcomes than single-session approaches. Maintenance treatments every 3–6 months are generally recommended to sustain results.
Microneedling Effectiveness
Interestingly, studies comparing microneedling to PRP have yielded surprising results. Controlled clinical trials indicated that microneedling alone produces similar hair parameter improvements as PRP therapy. In one study, researchers found that microneedling combined with minoxidil was more effective than minoxidil alone, with patients experiencing significant increases in hair count and thickness after weeks of treatment.
The mechanical stimulation provided by microneedling appears to activate stem cells in the hair bulge area, leading to regeneration of hair follicles. It also enhances blood flow to the scalp, delivering more nutrients and oxygen to the hair follicles.
Cost Breakdown
PRP Session Pricing
Professional PRP treatments for hair loss typically range from $500 to $2500 per session, with most reputable clinics charging around $1000 per treatment. This price reflects the specialized equipment, medical expertise, and time required to properly extract, process, and inject the platelet-rich plasma. Most treatment protocols recommend 3–4 initial sessions spaced 4–6 weeks apart, bringing the total initial costs to approximately $2000–$10,000.
Microneedling Costs
Professional microneedling sessions for hair loss typically cost between $200 and $700 per treatment, with an average price of about $300 per session. Like PRP, most protocols recommend 3–6 initial treatments spaced 4–6 weeks apart, resulting in a total initial cost of approximately $900–$1,800, considerably less than that of the PRP treatment.
For those seeking even more affordable options, at-home microneedling devices represent a significant cost-saving alternative. Quality derma rollers or stamps designed specifically for scalp use range from $30 to $200 for a one-time purchase. While these devices require personal commitment to proper technique and sterilization, they dramatically reduce the long-term cost of treatment.
Note: The price ranges mentioned above are approximate and subject to change over time and across different locations. Costs may vary based on factors such as pricing policies and the provider's experience.

Microneedling is generally more cost effective than PRP therapy.
Insurance Coverage
Unfortunately, both PRP and microneedling are generally considered cosmetic procedures for hair loss treatment, meaning they're typically not covered by health insurance. Some providers may offer financing options or payment plans to help make these treatments more accessible.
In rare cases, if hair loss is due to a specific medical condition or injury, insurance might provide partial coverage. It's always worth checking with your insurance provider and requesting a detailed explanation of benefits.
Side Effects

While both PRP and microneedling are considered safe when performed properly, they do come with potential side effects. (Image: Logolls; Istock)
Common PRP Reactions
Most PRP side effects are mild and temporary, resolving within a few days of treatment. The most common reactions include scalp tenderness and sensitivity at injection sites, mild swelling or bruising, headache in the hours following treatment, and temporary pinpoint bleeding. Some patients also experience a sensation of "tightness" in the scalp for 1–2 days after the procedure.
Microneedling Risks
Microneedling side effects are also generally mild and short-lived. Most patients experience redness and sensitivity of the treated area, similar to a mild sunburn, lasting 24–48 hours. Pinpoint bleeding during the procedure is normal and typically stops within minutes. Some patients notice flaking or dryness of the scalp for a few days as the microchannels heal.
Serious Complications
Serious complications from either treatment are rare when performed by qualified providers. However, potential risks include infection (particularly if proper sterilization protocols aren't followed), scarring (more common with deeper needle penetration or excessive pressure), granuloma formation (rare inflammatory reaction), and nerve damage (extremely rare and typically temporary when it does occur).
Some specific contraindications apply to both treatments. Neither should be performed on active scalp infections, open wounds, or in patients with bleeding disorders or who take blood thinners. Those with a history of keloid scarring should approach microneedling with caution and possibly opt for shallower needle depths.
Overall Comparison: PRP vs Microneedling
| Aspect | PRP (Platelet-Rich Plasma) | Microneedling |
|---|---|---|
| Mechanism | Delivers growth factors from your blood directly to hair follicles via concentrated platelets. | Creates controlled micro-injuries to trigger natural healing and growth factors. |
| Initial Cost | $500–$2500 per session | Professional: $200–$700 per session |
| Effectiveness | Increase in hair density after 3 sessions | Comparable results to PRP in clinical studies |
| Treatment Process | Blood draw → centrifuge → scalp injections Duration: 60–90 minutes | Fine needles create micro-punctures Duration: 45–60 minutes (professional) |
| Pain Level | Moderate (blood draw + injections) Topical numbing required | Mild (vibrating/pressure sensation) Topical numbing recommended |
| Common Side Effects | Scalp tenderness, mild swelling/bruising, headache, temporary bleeding | Redness (24–48 hrs), scalp sensitivity, pinpoint bleeding, temporary flaking |
| Results Timeline | Reduced shedding: 4–6 weeks Visible improvement: 3–4 months Max: 6–12 months | Reduced shedding: 4–6 weeks Visible improvement: 3–4 months Max: 6–12 months |
| Maintenance Frequency | Every 3–6 months | Professional: Every 1–3 months At-home: Every 3–4 weeks |
| Insurance Coverage | Generally not covered (cosmetic) | Generally not covered (cosmetic) |
Choose TryBello for Your Hair Restoration
While both PRP and microneedling show promising results, many people can achieve meaningful hair improvement through targeted topical treatments that work with your body's natural growth processes.

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Unlike clinical procedures that require monthly appointments and significant downtime, our hormone-free formula works continuously to nourish your scalp environment, requiring just 1–2 daily applications that integrate seamlessly into your existing routine.
With visible results typically appearing within 8 weeks and a 120-day growth guarantee, our approach allows you to invest in your hair health without the financial risk or invasive procedures of clinical treatments.
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